Air sealing makes your house tighter, and that's the point, but it also means less stray air reaching anything that burns gas. So before we seal a single gap, I look at your gas furnace, water heater and fireplace to be sure they'll still vent safely once the leaks are closed. If something looks off, we talk it through before any sealing starts.
Then we close up the leaks and leave alone the vents that are meant to breathe, like the ones at the eaves, along the ridge and at the gable ends. Those keep air moving through the attic, and burying them is how moisture ends up in the framing. Around hot flue pipes we use metal flashing and a high-heat sealant rather than regular foam.
Foam is the other way to go. Closed-cell foam insulation, a dense foam that also blocks moisture, seals and insulates in one pass, but it costs more. Below the floor it's a different job, and if your house sits over a basement, the rim joist, the band of wood where the house rests on the foundation, is a big leak we can seal as part of basement insulation.